SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib

We previously developed a hybrid small molecule SNIPER (Specific and Nongenetic IAP‐dependent Protein ERaser) against transforming acidic coiled‐coil‐3 (TACC3), SNIPER(TACC3), that induces proteasomal degradation of TACC3 protein. In this study, we found that SNIPER(TACC3) induces cytoplasmic vacuol...

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Bibliografische gegevens
Gepubliceerd in:Cancer Sci
Hoofdauteurs: Ohoka, Nobumichi, Nagai, Katsunori, Shibata, Norihito, Hattori, Takayuki, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448626/
https://ncbi.nlm.nih.gov/pubmed/28192613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13198
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