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Targeted Protein Degradation by Chimeric Small Molecules, PROTACs and SNIPERs
Technologies that induce targeted protein degradation by small molecules have been developed recently. Chimeric small molecules such as Proteolysis Targeting Chimeras (PROTACs) and Specific and Non-genetic IAP-dependent Protein Erasers (SNIPERs), and E3 modulators such as thalidomides, hijack the ce...
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| Publicado no: | Front Chem |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6914816/ https://ncbi.nlm.nih.gov/pubmed/31921772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00849 |
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