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Targeted Protein Degradation by Chimeric Small Molecules, PROTACs and SNIPERs
Technologies that induce targeted protein degradation by small molecules have been developed recently. Chimeric small molecules such as Proteolysis Targeting Chimeras (PROTACs) and Specific and Non-genetic IAP-dependent Protein Erasers (SNIPERs), and E3 modulators such as thalidomides, hijack the ce...
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| 出版年: | Front Chem |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6914816/ https://ncbi.nlm.nih.gov/pubmed/31921772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00849 |
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