Inward-facing conformation of a multidrug resistance MATE family transporter

Multidrug and toxic compound extrusion (MATE) transporters mediate excretion of xenobiotics and toxic metabolites, thereby conferring multidrug resistance in bacterial pathogens and cancer cells. Structural information on the alternate conformational states and knowledge of the detailed mechanism of...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Zakrzewska, Sandra, Mehdipour, Ahmad Reza, Malviya, Viveka Nand, Nonaka, Tsuyoshi, Koepke, Juergen, Muenke, Cornelia, Hausner, Winfried, Hummer, Gerhard, Safarian, Schara, Michel, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589766/
https://ncbi.nlm.nih.gov/pubmed/31160466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904210116
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