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Structure of a human multidrug transporter in an inward-facing conformation

Multidrug resistance protein 1 (ABCC1) is a member of the ‘C’ class of ATP-binding cassette transporters, which can give rise to resistance to chemotherapy via drug export from cells. It also acts as a leukotriene C4 transporter, and hence has a role in adaptive immune response. Most C-class members...

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Detalhes bibliográficos
Main Authors: Rosenberg, Mark F., Oleschuk, Curtis J., Wu, Peng, Mao, Qingcheng, Deeley, Roger G., Cole, Susan P.C., Ford, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232029/
https://ncbi.nlm.nih.gov/pubmed/20109555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2010.01.011
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