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Inward-facing conformation of a multidrug resistance MATE family transporter

Multidrug and toxic compound extrusion (MATE) transporters mediate excretion of xenobiotics and toxic metabolites, thereby conferring multidrug resistance in bacterial pathogens and cancer cells. Structural information on the alternate conformational states and knowledge of the detailed mechanism of...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Zakrzewska, Sandra, Mehdipour, Ahmad Reza, Malviya, Viveka Nand, Nonaka, Tsuyoshi, Koepke, Juergen, Muenke, Cornelia, Hausner, Winfried, Hummer, Gerhard, Safarian, Schara, Michel, Hartmut
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589766/
https://ncbi.nlm.nih.gov/pubmed/31160466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904210116
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