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Broadly conserved Na(+)-binding site in the N-lobe of prokaryotic multidrug MATE transporters

Multidrug and toxic-compound extrusion (MATE) proteins comprise an important but largely uncharacterized family of secondary-active transporters. In both eukaryotes and prokaryotes, these transporters protect the cell by catalyzing the efflux of a broad range of cytotoxic compounds, including human-...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ficici, Emel, Zhou, Wenchang, Castellano, Steven, Faraldo-Gómez, José D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142261/
https://ncbi.nlm.nih.gov/pubmed/29915058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802080115
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