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An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity
Multidrug efflux pumps present a challenge to treatment of bacterial infections, making it vitally important to understand their mechanism of action. Here we investigated the nature of substrate binding within LmrP of L. lactis, a prototypical multidrug transporter of the major facilitator superfami...
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| Pubblicato in: | Nat Struct Mol Biol |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7951658/ https://ncbi.nlm.nih.gov/pubmed/32719456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0464-y |
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