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Protonation drives the conformational switch in the multidrug transporter LmrP
Multidrug antiporters of the Major Facilitator Superfamily couple proton translocation to the extrusion of cytotoxic molecules. The conformational changes that underlie the transport cycle and the structural basis of coupling of these transporters have not been elucidated. Here we utilized extensive...
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| Publicado no: | Nat Chem Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4749020/ https://ncbi.nlm.nih.gov/pubmed/24316739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1408 |
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