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Protonation-dependent conformational dynamics of the multidrug transporter EmrE

The small multidrug transporter from Escherichia coli, EmrE, couples the energetically uphill extrusion of hydrophobic cations out of the cell to the transport of two protons down their electrochemical gradient. Although principal mechanistic elements of proton/substrate antiport have been described...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Dastvan, Reza, Fischer, Axel W., Mishra, Smriti, Meiler, Jens, Mchaourab, Hassane S.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747756/
https://ncbi.nlm.nih.gov/pubmed/26787875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520431113
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