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Lipid Composition Regulates the Orientation of Transmembrane Helices in HorA, an ABC Multidrug Transporter

ATP-binding cassette (ABC) transporters constitute a large class of molecular pumps whose central role in chemotherapy resistance has highlighted their clinical relevance. We investigated whether the lipid composition of the membrane affects the function and structure of HorA, a bacterial ABC multid...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gustot, Adelin, Smriti, Ruysschaert, Jean-Marie, Mchaourab, Hassane, Govaerts, Cédric
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863179/
https://ncbi.nlm.nih.gov/pubmed/20223819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.079673
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