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Lipid Composition Regulates the Orientation of Transmembrane Helices in HorA, an ABC Multidrug Transporter
ATP-binding cassette (ABC) transporters constitute a large class of molecular pumps whose central role in chemotherapy resistance has highlighted their clinical relevance. We investigated whether the lipid composition of the membrane affects the function and structure of HorA, a bacterial ABC multid...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863179/ https://ncbi.nlm.nih.gov/pubmed/20223819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.079673 |
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