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Hoechst 33342 Is a Hidden “Janus” amongst Substrates for the Multidrug Efflux Pump LmrP

Multidrug transporters mediate the active extrusion of antibiotics and toxic ions from the cell. This reaction is thought to be based on a switch of the transporter between two conformational states, one in which the interior substrate binding cavity is available for substrate binding at the inside...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Neuberger, Arthur, van Veen, Hendrik W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634932/
https://ncbi.nlm.nih.gov/pubmed/26540112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141991
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