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Multidrug Efflux Pumps and the Two-Faced Janus of Substrates and Inhibitors

Antibiotics are miracle drugs that can cure infectious bacterial diseases. However, their utility is challenged by antibiotic-resistant bacteria emerging in clinics and straining modern medicine and our ways of life. Certain bacteria such as Gram-negative (Gram(−)) and Mycobacteriales species are in...

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Bibliografische gegevens
Gepubliceerd in:Acc Chem Res
Hoofdauteurs: Zgurskaya, Helen I., Walker, John K., Parks, Jerry M., Rybenkov, Valentin V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208102/
https://ncbi.nlm.nih.gov/pubmed/33539084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.0c00843
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