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Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-TolC Multidrug Efflux Pump

Antibiotic resistance is a major threat to human welfare. Inhibitors of multidrug efflux pumps (EPIs) are promising alternative therapeutics that could revive activities of antibiotics and reduce bacterial virulence. Identification of new druggable sites for inhibition is critical for the developmen...

詳細記述

保存先:
書誌詳細
出版年:ACS Infect Dis
主要な著者: Abdali, Narges, Parks, Jerry M., Haynes, Keith M., Chaney, Julie L., Green, Adam T., Wolloscheck, David, Walker, John K., Rybenkov, Valentin V., Baudry, Jerome, Smith, Jeremy C., Zgurskaya, Helen I.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553321/
https://ncbi.nlm.nih.gov/pubmed/27768847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00167
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