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Structure of the AcrAB-TolC multidrug efflux pump

The capacity of numerous bacterial species to tolerate antibiotics and other toxic compounds arises in part from the activity of energy-dependent transporters. In Gram-negative bacteria, many of these transporters form multicomponent ‘pumps’ that span both inner and outer membranes and are driven en...

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書目詳細資料
發表在:Nature
Main Authors: Du, Dijun, Wang, Zhao, James, Nathan R., Voss, Jarrod E., Klimont, Ewa, Ohene-Agyei, Thelma, Venter, Henrietta, Chiu, Wah, Luisi, Ben F.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361902/
https://ncbi.nlm.nih.gov/pubmed/24747401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13205
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