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An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump
Bacterial efflux pumps confer multidrug resistance by transporting diverse antibiotics from the cell. In Gram-negative bacteria, some of these pumps form multi-protein assemblies that span the cell envelope. Here, we report the near-atomic resolution cryoEM structures of the Escherichia coli AcrAB-T...
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| Publicat a: | eLife |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5404916/ https://ncbi.nlm.nih.gov/pubmed/28355133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24905 |
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