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In situ structure and assembly of the multidrug efflux pump AcrAB-TolC
Multidrug efflux pumps actively expel a wide range of toxic substrates from the cell and play a major role in intrinsic and acquired drug resistance. In Gram-negative bacteria, these pumps form tripartite assemblies that span the cell envelope. However, the in situ structure and assembly mechanism o...
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| Pubblicato in: | Nat Commun |
|---|---|
| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6570770/ https://ncbi.nlm.nih.gov/pubmed/31201302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10512-6 |
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