In situ structure and assembly of the multidrug efflux pump AcrAB-TolC

Multidrug efflux pumps actively expel a wide range of toxic substrates from the cell and play a major role in intrinsic and acquired drug resistance. In Gram-negative bacteria, these pumps form tripartite assemblies that span the cell envelope. However, the in situ structure and assembly mechanism o...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Shi, Xiaodong, Chen, Muyuan, Yu, Zhili, Bell, James M., Wang, Hans, Forrester, Isaac, Villarreal, Heather, Jakana, Joanita, Du, Dijun, Luisi, Ben F., Ludtke, Steven J., Wang, Zhao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570770/
https://ncbi.nlm.nih.gov/pubmed/31201302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10512-6
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