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Dynamics of a bacterial multidrug ABC transporter in the inward- and outward-facing conformations

The study of membrane proteins remains a challenging task, and approaches to unravel their dynamics are scarce. Here, we applied hydrogen/deuterium exchange (HDX) coupled to mass spectrometry to probe the motions of a bacterial multidrug ATP-binding cassette (ABC) transporter, BmrA, in the inward-fa...

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Detalhes bibliográficos
Main Authors: Mehmood, Shahid, Domene, Carmen, Forest, Eric, Jault, Jean-Michel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390859/
https://ncbi.nlm.nih.gov/pubmed/22711831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204067109
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