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Dynamic distinctions in the Na(+)/Ca(2+) exchanger adopting the inward- and outward-facing conformational states
Na(+)/Ca(2+) exchanger (NCX) proteins operate through the alternating access mechanism, where the ion-binding pocket is exposed in succession either to the extracellular or the intracellular face of the membrane. The archaeal NCX_Mj (Methanococcus jannaschii NCX) system was used to resolve the backb...
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| Publicado en: | J Biol Chem |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5519378/ https://ncbi.nlm.nih.gov/pubmed/28572509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.787168 |
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