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Structure of an EIIC sugar transporter trapped in an inward-facing conformation

The phosphoenolpyruvate-dependent phosphotransferase system (PTS) transports sugar into bacteria and phosphorylates the sugar for metabolic consumption. The PTS is important for the survival of bacteria and thus a potential target for antibiotics, but its mechanism of sugar uptake and phosphorylatio...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ren, Zhenning, Lee, Jumin, Moosa, Mahdi Muhammad, Nian, Yin, Hu, Liya, Xu, Zhichun, McCoy, Jason G., Ferreon, Allan Chris M., Im, Wonpil, Zhou, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003338/
https://ncbi.nlm.nih.gov/pubmed/29784777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800647115
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