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Reversible Cation-Selective Attachment and Self-Assembly of Human Tau on Supported Brain Lipid Membranes

Misfolding and aggregation of the neuronal, microtubule-associated protein tau is involved in the patho-genesis of Alzheimer’s disease and tauopathies. It has been proposed that neuronal membranes could play a role in tau release, internalization, and aggregation and that tau aggregates could exert...

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Pubblicato in:Nano Lett
Autori principali: Mari, Stefania A., Wegmann, Susanne, Tepper, Katharina, Hyman, Bradley T., Mandelkow, Eva-Maria, Mandelkow, Eckhard, Müller, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588182/
https://ncbi.nlm.nih.gov/pubmed/29644863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.8b01085
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