Wordt geladen...
ATP binds and inhibits the neurodegeneration-associated fibrillization of the FUS RRM domain
Adenosine triphosphate (ATP) provides energy for cellular processes but has recently been found to act also as a hydrotrope to maintain protein homeostasis. ATP bivalently binds the disordered domain of FUS containing the RG/RGG sequence motif and thereby affects FUS liquid-liquid phase separation....
Bewaard in:
| Gepubliceerd in: | Commun Biol |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2019
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6586847/ https://ncbi.nlm.nih.gov/pubmed/31240261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0463-x |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|