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TMEM106B, a risk factor for FTLD and aging, has an intrinsically disordered cytoplasmic domain
TMEM106B was initially identified as a risk factor for FTLD, but recent studies highlighted its general role in neurodegenerative diseases. Very recently TMEM106B has also been characterized to regulate aging phenotypes. TMEM106B is a 274-residue lysosomal protein whose cytoplasmic domain functions...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | PLoS One |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6192649/ https://ncbi.nlm.nih.gov/pubmed/30332472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205856 |
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