Photoactivable Glycolipid Antigens Generate Stable Conjugates with CD1d for Invariant Natural Killer T Cell Activation

Activation of invariant natural killer T lymphocytes (iNKT cells) by α-galactosylceramide (α-GC) elicits a range of pro-inflammatory or anti-inflammatory immune responses. We report the synthesis and characterization of a series of α-GC analogues with acyl chains of varying length and a terminal ben...

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Bibliografiset tiedot
Julkaisussa:Bioconjug Chem
Päätekijät: Veerapen, Natacha, Kharkwal, Shalu Sharma, Jervis, Peter, Bhowruth, Veemal, Besra, Amareeta K., North, Simon J., Haslam, Stuart M., Dell, Anne, Hobrath, Judith, Quaid, Padraic J., Moynihan, Patrick J., Cox, Liam R., Kharkwal, Himanshu, Zauderer, Maurice, Besra, Gurdyal S., Porcelli, Steven A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586470/
https://ncbi.nlm.nih.gov/pubmed/30085659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00484
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