Cicero predicts cis-regulatory DNA interactions from single cell chromatin accessibility data

Linking regulatory DNA elements to their target genes, which may be located hundreds of kilobases away, remains challenging. Here we introduce Cicero, an algorithm that identifies coaccessible pairs of DNA elements using single-cell chromatin accessibility data, and so connects regulatory elements t...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Pliner, Hannah A., Packer, Jonathan, McFaline-Figueroa, José L., Cusanovich, Darren A., Daza, Riza, Aghamirzaie, Delasa, Srivatsan, Sanjay, Qiu, Xiaojie, Jackson, Dana, Minkina, Anna, Adey, Andrew, Steemers, Frank J., Shendure, Jay, Trapnell, Cole
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582963/
https://ncbi.nlm.nih.gov/pubmed/30078726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.06.044
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