Cicero predicts cis-regulatory DNA interactions from single cell chromatin accessibility data

Linking regulatory DNA elements to their target genes, which may be located hundreds of kilobases away, remains challenging. Here we introduce Cicero, an algorithm that identifies coaccessible pairs of DNA elements using single-cell chromatin accessibility data, and so connects regulatory elements t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell
Egile Nagusiak: Pliner, Hannah A., Packer, Jonathan, McFaline-Figueroa, José L., Cusanovich, Darren A., Daza, Riza, Aghamirzaie, Delasa, Srivatsan, Sanjay, Qiu, Xiaojie, Jackson, Dana, Minkina, Anna, Adey, Andrew, Steemers, Frank J., Shendure, Jay, Trapnell, Cole
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582963/
https://ncbi.nlm.nih.gov/pubmed/30078726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.06.044
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak