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Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics
Nuclear transport is facilitated by the Nuclear Pore Complex (NPC) and is essential for life in eukaryotes. The NPC is a long-lived and exceptionally large structure. We asked whether NPC quality control is compromised in aging mitotic cells. Our images of single yeast cells during aging, show that...
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| Pubblicato in: | eLife |
|---|---|
| Autori principali: | , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6579512/ https://ncbi.nlm.nih.gov/pubmed/31157618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48186 |
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