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Poor old pores—The challenge of making and maintaining nuclear pore complexes in aging

The nuclear pore complex (NPC) is the sole gateway to the nuclear interior, and its function is essential to all eukaryotic life. Controlling the functionality of NPCs is a tremendous challenge for cells. Firstly, NPCs are large structures, and their complex assembly does occasionally go awry. Secon...

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Bibliographische Detailangaben
Veröffentlicht in:FEBS J
Hauptverfasser: Rempel, Irina L., Steen, Anton, Veenhoff, Liesbeth M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7154712/
https://ncbi.nlm.nih.gov/pubmed/31912972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.15205
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