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Size-dependent leak of soluble and membrane proteins through the yeast nuclear pore complex
Nuclear pore complexes (NPCs) allow selective import and export while forming a barrier for untargeted proteins. Using fluorescence microscopy, we measured in vivo the permeability of the Saccharomyces cerevisiae NPC for multidomain proteins of different sizes and found that soluble proteins of 150...
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| Published in: | Mol Biol Cell |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Cell Biology
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4454183/ https://ncbi.nlm.nih.gov/pubmed/25631821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-07-1175 |
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