The β-Amyloid Precursor Protein of Alzheimer’s Disease Enhances Neuron Viability and Modulates Neuronal Polarity

β-Amyloid precursor protein (βPP) can reside at neuron and glial cell surfaces or undergo proteolytic processing into secreted fragments. Although βPP has been studied extensively, its precise physiological role is unknown. A line of transgenic knock-out mice selectively deficient in βPP survive and...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Perez, Ruth G., Zheng, Hui, Van der Ploeg, Lex H. T., Koo, Edward H.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573428/
https://ncbi.nlm.nih.gov/pubmed/9390996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-24-09407.1997
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