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Amyloid β precursor protein as a molecular target for amyloid β–induced neuronal degeneration in Alzheimer’s disease
A role of amyloid β (Aβ) peptide aggregation and deposition in Alzheimer’s disease (AD) pathogenesis is widely accepted. Significantly, abnormalities induced by aggregated Aβ have been linked to synaptic and neuritic degeneration, consistent with the “dying-back” pattern of degeneration that charact...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3762679/ https://ncbi.nlm.nih.gov/pubmed/23714735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.04.021 |
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