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The amyloid precursor protein: beyond amyloid
The amyloid precursor protein (APP) takes a central position in Alzheimer's disease (AD) pathogenesis: APP processing generates the β-amyloid (Aβ) peptides, which are deposited as the amyloid plaques in brains of AD individuals; Point mutations and duplications of APP are causal for a subset of...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2006
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1538601/ https://ncbi.nlm.nih.gov/pubmed/16930452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-1-5 |
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