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Biology and pathophysiology of the amyloid precursor protein
The amyloid precursor protein (APP) plays a central role in the pathophysiology of Alzheimer's disease in large part due to the sequential proteolytic cleavages that result in the generation of β-amyloid peptides (Aβ). Not surprisingly, the biological properties of APP have also been the subjec...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098799/ https://ncbi.nlm.nih.gov/pubmed/21527012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-27 |
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