Altered NMDAR signaling underlies autistic-like features in mouse models of CDKL5 deficiency disorder

CDKL5 deficiency disorder (CDD) is characterized by epilepsy, intellectual disability, and autistic features, and CDKL5-deficient mice exhibit a constellation of behavioral phenotypes reminiscent of the human disorder. We previously found that CDKL5 dysfunction in forebrain glutamatergic neurons res...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Commun
मुख्य लेखकों: Tang, Sheng, Terzic, Barbara, Wang, I-Ting Judy, Sarmiento, Nicolas, Sizov, Katherine, Cui, Yue, Takano, Hajime, Marsh, Eric D., Zhou, Zhaolan, Coulter, Douglas A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2019
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572855/
https://ncbi.nlm.nih.gov/pubmed/31201320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10689-w
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