A carregar...
Photoenzymatic Catalysis Enables Radical-Mediated Ketone Reduction in ‘Ene’-Reductases
Flavin-dependent ‘ene’-reductases (EREDs) are known to stereoselectively reduce activated alkenes, but are inactive toward carbonyls. Herein we demonstrate that in the presence of photoredox catalysts, these enzymes will reduce aromatic ketones. Mechanistic experiments suggest this reaction proceeds...
Na minha lista:
| Publicado no: | Angew Chem Int Ed Engl |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6570536/ https://ncbi.nlm.nih.gov/pubmed/30951226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201902005 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|