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Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics

Kistamicin is a divergent member of the glycopeptide antibiotics, a structurally complex class of important, clinically relevant antibiotics often used as the last resort against resistant bacteria. The extensively crosslinked structure of these antibiotics that is essential for their activity makes...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Greule, Anja, Izoré, Thierry, Iftime, Dumitrita, Tailhades, Julien, Schoppet, Melanie, Zhao, Yongwei, Peschke, Madeleine, Ahmed, Iftekhar, Kulik, Andreas, Adamek, Martina, Goode, Robert J. A., Schittenhelm, Ralf B., Kaczmarski, Joe A., Jackson, Colin J., Ziemert, Nadine, Krenske, Elizabeth H., De Voss, James J., Stegmann, Evi, Cryle, Max J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565677/
https://ncbi.nlm.nih.gov/pubmed/31197182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10384-w
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