The biosynthetic implications of late-stage condensation domain selectivity during glycopeptide antibiotic biosynthesis

Non-ribosomal peptide synthesis is a highly important biosynthetic pathway for the formation of many secondary metabolites of medical relevance. Due to the challenges associated with the chemical synthesis of many of the products of these assembly lines, understanding the activity and selectivity of...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Schoppet, Melanie, Peschke, Madeleine, Kirchberg, Anja, Wiebach, Vincent, Süssmuth, Roderich D., Stegmann, Evi, Cryle, Max J.
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2018
Teme:
Chemistry
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333238/
https://ncbi.nlm.nih.gov/pubmed/30713624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc03530j
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