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The biosynthetic implications of late-stage condensation domain selectivity during glycopeptide antibiotic biosynthesis

Non-ribosomal peptide synthesis is a highly important biosynthetic pathway for the formation of many secondary metabolites of medical relevance. Due to the challenges associated with the chemical synthesis of many of the products of these assembly lines, understanding the activity and selectivity of...

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Publicat a:Chem Sci
Autors principals: Schoppet, Melanie, Peschke, Madeleine, Kirchberg, Anja, Wiebach, Vincent, Süssmuth, Roderich D., Stegmann, Evi, Cryle, Max J.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333238/
https://ncbi.nlm.nih.gov/pubmed/30713624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc03530j
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