Biosynthesis of Chloro-β-Hydroxytyrosine, a Nonproteinogenic Amino Acid of the Peptidic Backbone of Glycopeptide Antibiotics

The role of the putative P450 monooxygenase OxyD and the chlorination time point in the biosynthesis of the glycopeptide antibiotic balhimycin produced by Amycolatopsis balhimycina were analyzed. The oxyD gene is located directly downstream of the bhp (perhydrolase) and bpsD (nonribosomal peptide sy...

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Bibliographische Detailangaben
Hauptverfasser: Puk, Oliver, Bischoff, Daniel, Kittel, Claudia, Pelzer, Stefan, Weist, Stefan, Stegmann, Efthimia, Süssmuth, Roderich D., Wohlleben, Wolfgang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Genetics and Molecular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC515157/
https://ncbi.nlm.nih.gov/pubmed/15342578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.18.6093-6100.2004
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