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Biosynthesis of Chloro-β-Hydroxytyrosine, a Nonproteinogenic Amino Acid of the Peptidic Backbone of Glycopeptide Antibiotics

The role of the putative P450 monooxygenase OxyD and the chlorination time point in the biosynthesis of the glycopeptide antibiotic balhimycin produced by Amycolatopsis balhimycina were analyzed. The oxyD gene is located directly downstream of the bhp (perhydrolase) and bpsD (nonribosomal peptide sy...

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Detalhes bibliográficos
Main Authors: Puk, Oliver, Bischoff, Daniel, Kittel, Claudia, Pelzer, Stefan, Weist, Stefan, Stegmann, Efthimia, Süssmuth, Roderich D., Wohlleben, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC515157/
https://ncbi.nlm.nih.gov/pubmed/15342578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.18.6093-6100.2004
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