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Synthesis of Nonproteinogenic Amino Acids to Probe Lantibiotic Biosynthesis

The synthesis of six nonproteinogenic amino acids appropriately protected for Fmoc-based solid phase peptide synthesis is described. These amino acids are (2S,3R)-vinylthreonine, (2S)-(E)-2-amino-5-fluoro-pent-3-enoic acid (fluoroallylglycine), (S)-β(2)-homoserine 3, (S) and (R)-β(3)-homocysteine, a...

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Detalhes bibliográficos
Main Authors: Zhang, Xingang, Ni, Weijuan, van der Donk, Wilfred A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525736/
https://ncbi.nlm.nih.gov/pubmed/16095288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo051182o
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