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In Vitro Biosynthesis of the Nonproteinogenic Amino Acid Methoxyvinylglycine

Oxyvinylglycines are a family of nonproteinogenic amino acids featuring an essential vinyl ether conferring mechanism-based inhibition of pyridoxal phosphate enzymes. The gene clusters for a few oxyvinylglycines are known, yet the biosynthetic origin of the vinyl ether is elusive. The in vitro biosy...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Patteson, Jon B., Dunn, Zachary D., Li, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180322/
https://ncbi.nlm.nih.gov/pubmed/29633497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201713419
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