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Investigation of the Substrate Specificity of Lacticin 481 Synthetase using Nonproteinogenic Amino Acids

Lantibiotics are peptide antimicrobial compounds that are characterized by the thioether-bridged amino acids lanthionine and methyllanthionine. For lacticin 481, these structures are installed in a two-step post-translational modification process by a bifunctional enzyme, lacticin 481 synthetase (Lc...

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Bibliografske podrobnosti
Main Authors: Levengood, Matthew R., Kerwood, Christopher C., Chatterjee, Champak, van der Donk, Wilfred A.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737179/
https://ncbi.nlm.nih.gov/pubmed/19222036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800752
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