Biosynthesis of Chloro-β-Hydroxytyrosine, a Nonproteinogenic Amino Acid of the Peptidic Backbone of Glycopeptide Antibiotics

The role of the putative P450 monooxygenase OxyD and the chlorination time point in the biosynthesis of the glycopeptide antibiotic balhimycin produced by Amycolatopsis balhimycina were analyzed. The oxyD gene is located directly downstream of the bhp (perhydrolase) and bpsD (nonribosomal peptide sy...

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Hlavní autoři: Puk, Oliver, Bischoff, Daniel, Kittel, Claudia, Pelzer, Stefan, Weist, Stefan, Stegmann, Efthimia, Süssmuth, Roderich D., Wohlleben, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Genetics and Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC515157/
https://ncbi.nlm.nih.gov/pubmed/15342578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.18.6093-6100.2004
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