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A proof-reading mechanism for non-proteinogenic amino acid incorporation into glycopeptide antibiotics
Non-ribosomal peptide biosynthesis produces highly diverse natural products through a complex cascade of enzymatic reactions that together function with high selectivity to produce bioactive peptides. The modification of non-ribosomal peptide synthetase (NRPS)-bound amino acids can introduce signifi...
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| Publicado no: | Chem Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6993612/ https://ncbi.nlm.nih.gov/pubmed/32055321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03678d |
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