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Biological, chemical, and biochemical strategies for modifying glycopeptide antibiotics

Since the discovery of vancomycin in the 1950s, the glycopeptide antibiotics (GPAs) have been of great interest to the scientific community. These nonribosomally biosynthesized peptides are highly cross-linked, often glycosylated, and inhibit bacterial cell wall assembly by interfering with peptidog...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Marschall, Edward, Cryle, Max J., Tailhades, Julien
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901329/
https://ncbi.nlm.nih.gov/pubmed/31672921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.006349
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