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Biological, chemical, and biochemical strategies for modifying glycopeptide antibiotics

Since the discovery of vancomycin in the 1950s, the glycopeptide antibiotics (GPAs) have been of great interest to the scientific community. These nonribosomally biosynthesized peptides are highly cross-linked, often glycosylated, and inhibit bacterial cell wall assembly by interfering with peptidog...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Marschall, Edward, Cryle, Max J., Tailhades, Julien
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901329/
https://ncbi.nlm.nih.gov/pubmed/31672921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.006349
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