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Biological, chemical, and biochemical strategies for modifying glycopeptide antibiotics

Since the discovery of vancomycin in the 1950s, the glycopeptide antibiotics (GPAs) have been of great interest to the scientific community. These nonribosomally biosynthesized peptides are highly cross-linked, often glycosylated, and inhibit bacterial cell wall assembly by interfering with peptidog...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Marschall, Edward, Cryle, Max J., Tailhades, Julien
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901329/
https://ncbi.nlm.nih.gov/pubmed/31672921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.006349
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