Inhibition of Ubiquitin-specific protease 14 suppresses cell proliferation and synergizes with chemotherapeutic agents in neuroblastoma

Neuroblastoma (NB) is the most common extracranial malignant solid tumor in children, and drug resistance is a major reason for poor outcomes. Elevated proteasome activity plays an important role in NB tumor development and resistance to conventional chemotherapy. Ubiquitin-specific protease 14 (USP...

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Bibliographic Details
Published in:Mol Cancer Ther
Main Authors: Yu, Yang, Zhao, Yanling, Fan, Yihui, Chen, Zhenghu, Li, Hui, Lu, Jiaxiong, Guo, Kevin, Woodfield, Sarah E., Vasudevan, Sanjeev A., Yang, Jianhua, Nuchtern, Jed G.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565366/
https://ncbi.nlm.nih.gov/pubmed/30962318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-0146
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