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Symbiotic macrophage-glioma cell interactions reveal synthetic lethality in PTEN null glioma
Heterotypic interactions across diverse cell types can enable tumor progression and hold the potential to expand therapeutic interventions. Here, combined profiling and functional studies of glioma cells in glioblastoma multiforme (GBM) models establish that PTEN deficiency activates YAP1, which dir...
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| izdano v: | Cancer Cell |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6561349/ https://ncbi.nlm.nih.gov/pubmed/31185211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.05.003 |
| Oznake: |
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