Symbiotic macrophage-glioma cell interactions reveal synthetic lethality in PTEN null glioma

Heterotypic interactions across diverse cell types can enable tumor progression and hold the potential to expand therapeutic interventions. Here, combined profiling and functional studies of glioma cells in glioblastoma multiforme (GBM) models establish that PTEN deficiency activates YAP1, which dir...

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Bibliografski detalji
Izdano u:Cancer Cell
Glavni autori: Chen, Peiwen, Zhao, Di, Li, Jun, Liang, Xin, Li, Jiexi, Chang, Andrew, Henry, Verlene K., Lan, Zhengdao, Spring, Denise J., Rao, Ganesh, Wang, Y. Alan, DePinho, Ronald A.
Format: Artigo
Jezik:Inglês
Izdano: 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561349/
https://ncbi.nlm.nih.gov/pubmed/31185211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.05.003
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